Are you watching life from the sidelines due to your PSC?

If you have primary sclerosing cholangitis, you may be eligible for the SPRING study which aims to improve liver function and could offer relief to PSC-related signs and symptoms.

I'm Interested

Can I Participate?

You may be able to participate in the SPRING clinical study if you:

I'm Interested

Are between 18 to 75 years old

Have a confirmed diagnosis of PSC for at least 6 months

Have taken PSC medication and are on a stable dosage for at least 12 weeks

Have high alkaline phosphatase (ALP) blood levels.  “High” can be defined at 1.5 times the upper limits of normal (ULN)

For patients with inflammatory bowel disease (IBD)*, it must be mild or in remission

You do not qualify if you have a stent in your bile duct.

*Your IBD must be controlled with medications or not significantly interfering with your life to be considered “mild”.
Other eligibility criteria apply.

CM-101 is an investigational drug for the treatment of primary sclerosing cholangitis.
CM-101 is being administered as an IV infusion in adult patients once every three weeks in the SPRING study.

By participating in this clinical research study, you will be seen by PSC experts,
help advance research about PSC, and may gain better management of your PSC symptoms.

What's Involved

STEP 1

Express Interest

Click here to see if you may qualify for the study.
STEP 2

Phone Call

Upon initial eligibility, a PatientWing representative will call you and guide you through additional eligibility questions.
STEP 3

Official Screening

The team at a participating study center will determine if you are eligible to participate in the study.
STEP 4

Study

Throughout the study, you will visit the site once every 3 weeks, for up to 16 treatments.

What You May Receive

By enrolling in this study, you may receive:

Study related treatment at no cost
Medical care related to PSC from physicians with experience in managing PSC
Travel reimbursement for study visits
Compensation for your time
See If You May Qualify

Why Should I Participate?

You could potentially see improvement in your overall liver health and potential relief for some of your symptoms.

Your participation in this study may help to advance research and understanding of PSC.

Learn More

Why Should I Participate?

You could potentially see improvement in your liver function and relief to your symptoms in the following ways:

Reduced inflammation
Decreased fatigue
Less severe itching

Your participation in this study may help to advance research and understanding of PSC.

Frequently Asked Questions

How do I get started?

Click here and enter your information to express interest in the study.

Where is the study conducted?

The study is being conducted at many research sites globally.

How will the potential treatment be taken?

The study drug treatment will be given through a drip into one of your blood vessels (via IV infusion), once every 3 weeks, for up to 16 treatments. Each infusion will take about 60 minutes.

Is there any cost for me to participate?

You will not have to pay for the study drug, visits, or for the procedures needed for you to take part in this study. The study sponsor will pay for the costs of the study drug and any tests or procedures needed.

Will I receive compensation?

You will be compensated for time and travel related to study visits. For more information, please talk to your study doctor.

Do I need health insurance?

No, health insurance is not needed to participate in the SPRING study.  There are no costs to participate.

Why didn’t I qualify?

Research studies are designed in specific ways to test the study drug for safety and effectiveness. An answer you provided was outside the guidelines for participating in this trial. This does not mean you will not qualify for other research studies.

What is the study drug being tested? How does it work?

The study drug is known as CM-101. CM-101 aims to reduce inflammation and fibrosis of the liver by inhibiting the excessive response of immune cells and fibroblast activation to irritation or injury.

Is there a chance I will receive a placebo?

Yes, you will have about a 30% chance of receiving a placebo for your treatment. All patients will be eligible to participate in an open-label extension (OLE) where those who qualify will receive the study drug with no chance of placebo.

About The Study Team

About The Sponsor

Chemomab is a clinical-stage biotechnology company focusing on the discovery and development of innovative therapeutics for fibrotic and inflammatory diseases with high unmet need.

About PatientWing

Our mission to bring better treatments to more people faster starts with you. We help sponsors find patients to participate in their clinical studies. With our focus on rare diseases and expertise in navigating the enrollment process, we're here for you every step of the way. To learn more, visit patientwing.com.

Have questions?

Call, email us or fill out the form. We're here to help.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Stay Connected

Get our latest stories & updates in your inbox.

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Back
to Top
See If You May Qualify